Genotyping Core Facility

The main aim of this unit is to provide genotyping for DNA Analysis and expression profiling using the Affymetrix GeneChip technology, accelerating the genetic research and enables the researchers to develop the diagnostic tools and tailor treatments for individual patients by identifying and measuring the genetic information associated with mendelian and complex disorders.

The data generated from the core facility is used for linkage analysis, population studies, Cytogenetic research, and differential gene expression.

The Laboratory has been processing both DNA and RNA microarrays. The DNA microarrays are used to study the linkage analysis, homozygosities, LOH, Copy number Studies, known and novel chromosomal aberrations, uniparental disomy (UPD), and regions identical-by-descent and Genetic Association studies where the RNA microarrays can be used to study the altered gene expression, altered Isoform expression and altered gene regulation.