Project Summary
Surgical wound infections remain a major postoperative risk, often linked to inadequate sealing methods. Traditional sutures are time-consuming, can damage tissue, and fail to provide immediate waterproof closure. Existing surgical sealants offer limited adhesion, poor mechanical strength and cytotoxicity, especially in wet and dynamic biological environments. We are developing synthetic polymeric biomaterials with precisely defined chemical architectures to overcome these limitations. The next-generation surgical sealants/adhesives/glues are engineered for strong tissue bonding, biocompatibility, and robust performance in biological conditions, addressing the critical gaps in surgical wound management and advancing clinical outcomes.
Other Projects by Jackie Ying
- Peptide-Based Radiopharmaceuticals.
- Peptide-Based Cancer Nanovaccines.
- Antimicrobial Peptides.
- Novel Organic and Inorganic Antimicrobial Materials.
- Targeted RNA Therapeutics for Genetic, Infectious and Oncologic Diseases.
- Unnatural Oligonucleotides for RNA Therapeutics.
- CAR-T Cells for Treating Acute Myeloid Leukemia.
- Synthetic Cell Culture Substrates.
- Antibiofouling Nano-Coatings for Medical Implants.
- Diagnostic Panels for Pediatric Sarcomas.
- Liquid Biopsy Diagnostics, Targeted Sequencing, and qPCR and dPCR Panels.
- Molecular Diagnostics for Pathogens in Organ Transplant.
- One Health Wastewater Surveillance of Viral Pathogens.
- Lateral Flow Assays for Rapid Detection of Invasive Aspergillosis.
- Mapping Seizure Behaviors to the Anterior/Mid-Cingulate–Insula Network.
- From Heart Failure to Holistic Cardiac: CardioScope AI-ECG Platform.
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