Project Summary

Surgical wound infections remain a major postoperative risk, often linked to inadequate sealing methods. Traditional sutures are time-consuming, can damage tissue, and fail to provide immediate waterproof closure. Existing surgical sealants offer limited adhesion, poor mechanical strength and cytotoxicity, especially in wet and dynamic biological environments. We are developing synthetic polymeric biomaterials with precisely defined chemical architectures to overcome these limitations. The next-generation surgical sealants/adhesives/glues are engineered for strong tissue bonding, biocompatibility, and robust performance in biological conditions, addressing the critical gaps in surgical wound management and advancing clinical outcomes.
Beta Version